With two similar-sounding names, Hodgkin lymphoma and non-Hodgkin lymphoma can easily be confused. Lymphoma is a form of cancer that affects the lymphocytes, a type of white blood cell that plays an important role in the immune system.
The primary difference between these two categories of lymphatic cancer is the type of lymphocyte that is affected. Hodgkin lymphoma is marked by the presence of Reed-Sternberg cells, which a physician can identify using a microscope.
In non-Hodgkin lymphoma, these cells are not present. In addition to the presence or lack of Reed-Sternberg cells, other differences between Hodgkin and non-Hodgkin lymphoma include that:.
Despite the many differences between these two types of lymphatic cancer, both have similar symptoms, such as enlarged lymph nodes, fatigue, weight loss and fever. If you notice any of these symptoms, it is important to consult with a physician.
Treatment for Hodgkin or non-Hodgkin lymphoma will depend on the type of lymphatic cancer you have, its stage, your overall health and many other factors. At Moffitt Cancer Center, the multispecialty experts that make up our Malignant Hematology Program collaborate as a tumor board to review patient cases, ensuring each patient receives an individualized treatment plan that addresses his or her unique needs.
It can range from observation only, to chemotherapy, immunotherapy and most recently cellular therapy. The first sign of the disease is often the appearance of enlarged lymph nodes. Non-Hodgkin lymphoma, by contrast, can be derived from B cells or T cells and can arise in the lymph nodes as well as other organs.
The median age of patients with non-Hodgkin lymphoma is 60, but it occurs in all age groups. Hodgkin lymphoma most often occurs in people ages 15 to 24 and in people over There are more than 60 distinct types of non-Hodgkin lymphoma, whereas Hodgkin lymphoma is a more homogeneous disease. Hodgkin lymphomas are more likely to arise in the upper portion of the body the neck, underarms, or chest. Non-Hodgkin lymphoma can arise in lymph nodes throughout the body, but can also arise in normal organs.
Patients with either type can have symptoms such as weight loss, fevers, and night sweats. The diseases often follow different courses of progression. Hodgkin lymphoma tends to progress in an orderly fashion, moving from one group of lymph nodes to the next, and is often diagnosed before it reaches an advanced stage.
Most patients with non-Hodgkin lymphoma are diagnosed at a more advanced stage. Treatments vary depending on the type of disease, its aggressiveness, and location, along with the age and general health of the patient. As a general rule, however, Hodgkin lymphoma is considered one of the most treatable cancers, with more than 90 percent of patients surviving more than five years.
Survival rates for patients with non-Hodgkin lymphoma tend to be lower, but for certain types of the disease, the survival rates are similar to those of patients with Hodgkin lymphoma. Various kinds of white blood cells are found within lymph and help fight disease within the body. Though, even with this understanding, lymphoma throws another wrench into the gears.
Reed-Sternberg cells are giant cells found in lymph fluid. They are relatively easy to identify under the microscope due to the fact that they are so large and often contain more than one nucleus.
Both forms of lymphoma are relatively rare. There are an estimated 70, new cases per year in the United States. It is estimated that there are only 8, new cases each year nationwide. The most common symptom is swelling of the lymph nodes in the abdomen, groin, neck, or underarm.
Other symptoms may include an enlarged spleen or liver, fever, weight loss, sweating and chills, and fatigue. From there, it often progresses in a predictable fashion moving from one group of lymph nodes to the next.
Progressing in such an orderly fashion allows the cancer to be detected and treated at an early stage. While recognizing each varying form of lymphoma is a feat in itself, knowing the difference between the two types will provide a strong understanding of this particular blood cancer. For more information on lymphoma, or to find out the latest research, visit www. Hi i am kavin, its my first occasion to commenting anywhere, when i read this post i thought i could also create comment due to this sensible paragraph.
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